- Down Syndrome Association of Orange County - Non-profit organization providing support and information to families, educators, doctors, hospitals, lawyers, geneticists, and family planners.
- Irvine Health Foundation - A non-profit grantmaking foundation whose goal is to improve the health and well-being of the residents of Orange County. Publications, lectures, and information about grant applications.
- Marijuana Anonymous District 5 - A fellowship sharing experience, strength, and hope to solve their common problem and help others to recover from marijuana addiction.
- Orange County Health Needs Assessment - A collaboration of public and private sector policymakers that attempt to conduct a comprehensive health assessment of Orange County. Executive Summary, history, and monthly newsletters.
- Orange County Medical Association - Professional organization for physicians. Activities, membership information, and legislative updates.
- The HealthCare Foundation For Orange County - The Foundation's mission is to improve the health of the neediest and most underserved residents of Orange County. Includes programs, calendar, investing and volunteer opportunities.
